Etiologi Gagal Hati

Oleh :

dr. Katherine Gowary Sugiarto

Etiologi gagal hati meliputi hepatotoksisitas akibat paracetamol, drug-induced liver injury (DILI), infeksi virus hepatitis maupun nonhepatotropik, penyakit autoimun, oklusi vaskular, hepatitis iskemik, Wilson Disease, infiltrasi keganasan, serta kehamilan. Sedangkan gagal hati acute on chronic dipengaruhi dua faktor yakni intrahepatik (hepatitis akut dan alcohol) dan ekstrahepatik (infeksi).[6,8]

Etiologi Gagal Hati Akut

Etiologi gagal hati akut meliputi berbagai hal di bawah ini.

Referensi

4. Friedman LS and Paul M. Handbook of liver disease. 4th ed. Philadelphia:Elsevier. 2018.
6. Radu-Ionita F, Pyscopoulos NT, Jinga M, Tintoiu IO, Sun Z, Bontas E. Liver disease: a multidisciplinary textbook. Switzerland: Springer Nature Switzerland AG. 2020.
8. Hernaez R, Solà E, Moreau R, Ginès P. Acute-on-chronic liver failure: an update. Gut. 2017; 66(3):541-53.
9. Ferri FF. Ferri’s clinical advisor. Philadelphia: Elsevier. 2019.
14. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Acute Liver Failure. https://www.ncbi.nlm.nih.gov/books/NBK548171/
15. Manka P, Verheyen J, Gerken G, Canbay A. Liver failure due to acute viral hepatitis (A-E). Visc Med. 2016;32:80-5.
16. Brewer EC and Hunter L. Acute liver failure due to disseminated varicella zoster infection. Case Report in Hepatology. 2018; 2018:1-5
17. Parekh J, Matei VM, Canas-Coto A, Friedman D, Lee WM. Budd-Chiari syndrome causing acute liver failure: A multicenter case series. Liver Transpl. Feb 2017;23(2):`135-42.
18. Zhang Y, Jiang H, Wei Y, Song B. Sinusoidal obstruction syndrome: A systemic review of etiologies, clinical symptoms, and magnetic resonance imaging features. World J Clin Cases. 2019; 7(18): 2746-59.
19. Soleimanpour H, SafariS, Rahmani F, Nejabatian A, Moayed A. Hepatic shock differential diagnosis and risk factors: A Review Article. Hepat Mon. 2015 Oct; 15(10): e27063.
20. Waseem N, Chen PH. Hypoxic hepatitis: A review and clinical update. J Clin Transl Hepatol. 2016; 4(3): 263-8.
21. Schilsky ML. Wilson disease: Clinical manifestations, diagnosis, and treatment. Clin Liver Dis (Hoboken). 2014 May 27;3(5):104-107. doi: 10.1002/cld.349. PMID: 30992899; PMCID: PMC6448712.
22. Gilroy RK. Wilson disease. Medscape. 2019.https://emedicine.medscape.com/article/183456-overview#
23. Pandey CK, Karna ST, Pandey VK, Tandon M. Acute liver failure in pregnancy: Challenges and management. Indian J Anesth. 2015 Mar; 59(3):144-9.
24. Solà E anda Fernandez J. Acute-on-chronic liver failure: The role of precipitating illness. SEMINARS IN Liver Disease. 2016;36(2):117-21.

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