Penatalaksanaan Inkompatibilitas Rhesus

Oleh :

dr. Felicia

Tujuan penatalaksanaan pada inkompatibilitas rhesus adalah untuk memastikan kesehatan bayi dan mengurangi risiko kehamilan yang akan datang. Adanya rekomendasi penggunaan imunoglobulin anti-D (anti-Rh) pada ibu yang berisiko tersensitisasi, dilaporkan telah mengurangi angka komplikasi hemolytic disease of the newborn (HDN). [13]

Terapi Farmakologis

Pada inkompatibilitas rhesus (Rh), terapi farmakologis yang paling dianjurkan adalah pemberian profilaksis imunoglobulin anti-D (anti-R). [13]

Referensi

5. Agarwal K, Rana A, Ravi AK. Treatment and Prevention of Rh Isoimmunization. J Fetal Med. 2014 Jun 1;1(2):81–8.
6. Bi S-H, Jiang L-L, Dai L-Y, et al. Rh-incompatible hemolytic disease of the newborn in Hefei. World J Clin Cases. 2019 Oct 26;7(20):3202–7.
8. Idi HT, Awwalu S, Abjah U, et al. Association of ABO neo-maternal incompatibility and neonatal jaundice in Nguru, Nigeria. Niger J Basic Clin Sci. 2019 Jan 1;16(1):51.
9. Mukhtar. Frequencies of ABO and Rhesus (D) blood group phenotypes among pregnant women attending antenatal clinic at Murtala Muhammad Specialist Hospital, Kano, Nigeria. Available from: http://www.jmedtropics.org/article.asp?issn=2276-7096;year=2019;volume=21;issue=1;spage=31;epage=36;aulast=Mukhtar
12. Celik K, Koker SA, Ozkul M, et al. Hong Kong Journal of Paediatrics [HK J Paediatr (New Series) 2019;24:120-126]. Available from: http://www.hkjpaed.org/details.asp?id=1239&show=1234
13. Silver R. Practice Bulletin No. 181: Prevention of Rh D Alloimmunization. Obstet Gynecol. 2017 Aug;130(2):e57.
16. Chacham S, Reddy DS, Reddy UN, et al. Neonatal Outcomes of Rh-Negative Pregnancies in a Tertiary Level Neonatal Intensive Care Unit: A Prospective Study. J Compr Pediatr. 2016 Aug 1;7(3). Available from: http://comprped.com/en/articles/19862.html
18. Tugcu AU, Ince DA, Turan O, et al. Hemolytic anemia caused by non-D minor blood incompatibilities in a newborn. Pan Afr Med J. 2019 29;33(262). Available from: https://www.panafrican-med-journal.com/content/article/33/262/full/
19. Shrba SA, Saheb BH. Factors Affecting Rh Isoimmunization and Suggested Protective Measures. Med J Babylon, 2013. 10(4):12.
21. Kaur D, Sidana P, Mandhan G, et al. Oblivious of the yellow world – A newborn’s telltale: ABO hemolytic disease of newborn. Glob J Transfus Med. 2019;4(1):87–9.
24. Mayer B, Hinkson L, Hillebrand W, et al. Efficacy of Antenatal Intravenous Immunoglobulin Treatment in Pregnancies at High Risk due to Alloimmunization to Red Blood Cells. Transfus Med Hemotherapy. 2018;45(6):429–36.
25. Ree IM, Simts-Wintjens VE, Bom JG van der, et al. Neonatal management and outcome in alloimmune hemolytic disease. J Expert Rev Hematol. 2017 Jun 5;10(7):607–16.
26. Bek SG, Eren N, Uzay A, et al. Rh (D) alloimmunization treated by double filtration plasmapheresis. Transfus Apher Sci. 2019 Feb 1;58(1):83–6.

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Masuk atau Daftar

Nomor Ponsel Sudah Terdaftar

Masuk dengan Email

Masuk dengan Email

Masuk dengan Facebook

Penatalaksanaan Inkompatibilitas Rhesus

Referensi

Masuk atau Daftar