Indikasi dan Dosis Penicillin Benzathine

Oleh :

dr.Shofa Nisrina Luthfiyani

Indikasi penicillin benzathine adalah pengobatan infeksi akibat bakteri gram positif. Umumnya, obat ini digunakan untuk mencegah terjadinya demam reumatik atau glomerulonefritis pasca infeksi streptokokus grup A di saluran napas atas. Penicillin juga digunakan untuk terapi sifilis, terutama pada ibu hamil.[1,2,4]

Infeksi Saluran Pernapasan Atas dan Profilaksis Primer Demam Reumatik

Penicillin benzathine dapat digunakan untuk infeksi saluran pernapasan atas (ISPA), termasuk faringitis akibat Infeksi Streptokokus Grup A. Obat ini juga digunakan sebagai profilaksis primer demam reumatik.

Referensi

1. National Center for Biotechnology Information. PubChem Compound Summary for CID 656811, Penicillin G benzathine. 2022. https://pubchem.ncbi.nlm.nih.gov/compound/Penicillin-G-benzathine.Copy
2. Gartlan WA, Reti K. Benzathine Penicillin. Treasure Island (FL): StatPearls Publishing; 2019 Jan. https://www.ncbi.nlm.nih.gov/books/NBK507723/
4. Prescribers’ Digital Reference. Penicillin G benzathine – drug summary. 2019. https://www.pdr.net/drug-summary/Bicillin-L-A-penicillin-G-benzathine-283#11
11. Gerber MA, Baltimore RS, et al. Prevention of rheumatic fever and diagnosis and treatment of acute streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research. Circulation 2009;119:1541-1551
12. Shulman ST, Bisno AL, Clegg HW, et al. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis 2012;15:1279-1282
13. Centers for Disease Control and Prevention (CDC). Epidemiology and Prevention of Vaccine-Preventable Diseases, The Pink Book, 12th Edition. May 2012
14. Centers for Disease Control and Prevention (CDC). Sexually Transmitted Diseases Treatment Guidelines 2015. MMWR. 2015;64(3):1-137
15. Panel on Opportunistic Infections in HIV-Infected Adults and Adolescents. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from the Centers for Disease Control and Prevention, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. http://aidsinfo.nih.gov/guidelines
16. Panel on Opportunistic Infections in HIV-Exposed and HIV-infected Children. Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-exposed and HIV-infected children: Department of Health and Human Services. Accessed Sept 9, 2019. https://aidsinfo.nih.gov/contentfiles/lvguidelines/oi_guidelines_pediatrics.pdf
17. Mitjà O, Asiedu K, Mabey D. Yaws. Lancet. 2013 Mar 2;381(9868):763-73. doi: 10.1016/S0140-6736(12)62130-8. Epub 2013 Feb 13. PMID: 23415015.

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