Epidemiologi Polyendocrine Metabolic Ovarian Syndrome

Oleh :

dr.Bedry Qintha

Menurut data epidemiologi, polyendocrine metabolic ovarian syndrome atau PMOS, yang sebelumnya disebut polycystic ovary syndrome/PCOS atau sindrom ovarium polikistik, memengaruhi 10-13% wanita usia reproduktif. Penyakit ini bisa ditemukan di usia reproduktif berapapun, tetapi banyak ditemukan pada kelompok usia 20-30 tahun. PMOS menyebabkan 0,43 juta disability-adjusted life years (DALYs) pada wanita usia reproduktif.[8,9]

Global

PMOS diperkirakan memengaruhi 10-13% wanita usia reproduktif di seluruh dunia. Meski dapat terdiagnosis pada usia reproduktif berapapun, PMOS paling banyak ditemukan pada kelompok usia 20-30 tahun.[8,9]

Referensi

1. Teede HJ, Khomami MB, Morman R, et al; Global Name Change Consortium. Polyendocrine metabolic ovarian syndrome, the new name for polycystic ovary syndrome: a multistep global consensus process. Lancet. 2026 May 12:S0140-6736(26)00717-8. doi: 10.1016/S0140-6736(26)00717-8.
2. Teede HJ, Tay CT, Laven J, et al. International evidence-based guideline for the assessment and management of polycystic ovary syndrome 2023. Melbourne: Monash University; 2023. https://www.monash.edu/__data/assets/pdf_file/0003/3371133/PCOS-Guideline-Summary-2023.pdf
3. Geraci G, Riccio C, Oliva F, et al. Women with PCOS have a heightened risk of cardiometabolic and cardiovascular diseases: statement from the Experts Group on Inositol in Basic and Clinical Research and PCOS (EGOI-PCOS) and Italian Association of Hospital Cardiologists (ANMCO). Front Cardiovasc Med. 2025 Sep 2;12:1520490. doi: 10.3389/fcvm.2025.1520490.
4. Prosperi S, Chiarelli F. Insulin resistance, metabolic syndrome and polycystic ovaries: an intriguing conundrum. Front Endocrinol (Lausanne). 2025 Oct 1;16:1669716. doi: 10.3389/fendo.2025.1669716.
7. Siddiqui S, Mateen S, Ahmad R, Moin S. A brief insight into the etiology, genetics, and immunology of polycystic ovarian syndrome (PCOS). J Assist Reprod Genet. 2022 Nov;39(11):2439-2473. doi: 10.1007/s10815-022-02625-7.
8. Singh S, Pal N, Shubham S, Sarma DK, Verma V, Marotta F, Kumar M. Polycystic Ovary Syndrome: Etiology, Current Management, and Future Therapeutics. J Clin Med. 2023 Feb 11;12(4):1454. doi: 10.3390/jcm12041454.
9. Joham AE, Rees DA, Shinkai K, Forslund M, Tay CT, Teede HJ. POLYCYSTIC OVARY SYNDROME: ORIGINS AND IMPLICATIONS: Epidemiological aspects of polycystic ovary syndrome. Reproduction. 2025 Jul 22;170(2):e250121. doi: 10.1530/REP-25-0121.
10. Salari N, Nankali A, Ghanbari A, Jafarpour S, Ghasemi H, Dokaneheifard S, Mohammadi M. Global prevalence of polycystic ovary syndrome in women worldwide: a comprehensive systematic review and meta-analysis. Arch Gynecol Obstet. 2024 Sep;310(3):1303-1314. doi: 10.1007/s00404-024-07607-x.
11. Lin L, Li W, Xu B, Li Y, Li J, Kong X, Du X. Global trends in polycystic ovarian syndrome over 30 years: an age-period-cohort study of 204 countries and territories (1990-2021). J Health Popul Nutr. 2025 Jul 8;44(1):242. doi: 10.1186/s41043-025-01002-1.
12. Deswal R, Narwal V, Dang A, Pundir CS. The Prevalence of Polycystic Ovary Syndrome: A Brief Systematic Review. J Hum Reprod Sci. 2020;13(4):261-271. doi:10.4103/jhrs.JHRS_95_18
13. Piltonen TT, Arffman RK, Joham AE. Natural history of polycystic ovary syndrome and new advances in the epidemiology. Seminars in Reproductive Medicine 2021 Jul (Vol. 39, No. 03/04, pp. 094-101).
14. Sumapraja K, Pangastuti N. Profile of Policystic Ovarian Syndrome Patients in Dr. Cipto Mangunkusumo General Hospital Jakarta March 2009 - March 2010. Indonesian Journal of Obstetrics and Gynecology, 2011;35(1)

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